The German doctor Katrin Berger (Christine Neubauer), together with Sam Vanderloo (Francis Fulton-Smith) runs a bush hospital in Namibia. After the sudden and unexpected death of her husband a year ago Katrin took over the task that he had begun and also looks after his two children from a previous marriage, Lindiwe (Ronja Forcher) and Neo (Pascal Andres). Sam loves Katrin, but from respect for the memory of his dead friend he keeps his feelings to himself. But one day, when Christian Lindenburg (Götz Otto) is brought into the hospital and immediately begins to flirt with Katrin, Sam’s jealousy is aroused. And Katrin seems to find this new patient, who has made a small fortune with a goldmine he inherited, completely charming. However, soon their attention is distracted by a curious incident: one day she finds dead antelopes at a waterhole. An examination indicates that the animals died from cyanide poisoning. And Christian's goldmine is the only possible source of the chemicals. Hardly have Katrin and Sam succeeded in averting the fatal danger for people and animals when Sam has a car accident in the wilderness and is bitten by a poisonous snake. It looks as though help cannot be fetched quickly enough. And now Katrin decides to stake everything on one desperate gamble: although she has only had a few flying lessons, she sets off in a small plane to fetch the serum which will save Sam's life.